Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates

During vertebrate gastrulation, mesoderm is induced in pluripotent cells, concomitant with dorsal‐ventral patterning and establishing of the dorsal axis. We applied single‐cell chromatin accessibility and transcriptome analyses to explore the emergence of cellular heterogeneity during gastrulation i...

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Detalles Bibliográficos
Autores principales: Bright, Ann Rose, van Genesen, Siebe, Li, Qingqing, Grasso, Alexia, Frölich, Siebren, van der Sande, Maarten, van Heeringen, Simon J, Veenstra, Gert Jan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090851/
https://www.ncbi.nlm.nih.gov/pubmed/33555045
http://dx.doi.org/10.15252/embj.2020104913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090851/
https://www.ncbi.nlm.nih.gov/pubmed/33555045
http://dx.doi.org/10.15252/embj.2020104913

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