Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis

Telomere fusions lead to a state of genomic instability, and are thought to drive clonal evolution and tumorigenesis. Telomere fusions occur via both Classical and Alternative Non-Homologous End Joining repair pathways. AsiDNA is a DNA repair inhibitor that acts by mimicking a DNA double strand brea...

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Detalles Bibliográficos
Autores principales: Subecz, Chloé, Sun, Jian-Sheng, Roger, Lauréline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091035/
https://www.ncbi.nlm.nih.gov/pubmed/33480989
http://dx.doi.org/10.1093/hmg/ddab008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091035/
https://www.ncbi.nlm.nih.gov/pubmed/33480989
http://dx.doi.org/10.1093/hmg/ddab008

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