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Imputing single-cell RNA-seq data by combining graph convolution and autoencoder neural networks
Single-cell RNA sequencing technology promotes the profiling of single-cell transcriptomes at an unprecedented throughput and resolution. However, in scRNA-seq studies, only a low amount of sequenced mRNA in each cell leads to missing detection for a portion of mRNA molecules, i.e. the dropout probl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091052/ https://www.ncbi.nlm.nih.gov/pubmed/33997678 http://dx.doi.org/10.1016/j.isci.2021.102393 |