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O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport

Macromolecular transport across the nuclear envelope depends on facilitated diffusion through nuclear pore complexes (NPCs). The interior of NPCs contains a permeability barrier made of phenylalanine-glycine (FG) repeat domains that selectively facilitates the permeation of cargoes bound to nuclear...

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Detalles Bibliográficos
Autores principales: Yoo, Tae Yeon, Mitchison, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091080/
https://www.ncbi.nlm.nih.gov/pubmed/33909044
http://dx.doi.org/10.1083/jcb.202010141