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O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport
Macromolecular transport across the nuclear envelope depends on facilitated diffusion through nuclear pore complexes (NPCs). The interior of NPCs contains a permeability barrier made of phenylalanine-glycine (FG) repeat domains that selectively facilitates the permeation of cargoes bound to nuclear...
Autores principales: | Yoo, Tae Yeon, Mitchison, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091080/ https://www.ncbi.nlm.nih.gov/pubmed/33909044 http://dx.doi.org/10.1083/jcb.202010141 |
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