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Evaluating the Role of STAT3 in CD4(+) T Cells in Susceptibility to Invasive Aspergillosis

We aimed to determine whether T cell-specific STAT3 deletion influences the immune response to Aspergillus in the immunosuppressed context in CD4(Stat3)(−/−) mice. Immunosuppressed and nonimmunosuppressed CD4(Stat3)(−/−) mice and littermate Stat3(flox/flox) (Stat3(fl/fl)) mice were infected with Asp...

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Detalles Bibliográficos
Autores principales: Gohir, Wajiha, McTaggart, Lisa, Kus, Julianne V., Mazzulli, Tony, Kumar, Deepali, Humar, Atul, Husain, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091102/
https://www.ncbi.nlm.nih.gov/pubmed/33526558
http://dx.doi.org/10.1128/IAI.00035-21