Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8(+) T cells in skin

Tissue-resident memory T cells (T(RM) cells) are key elements of tissue immunity. Here, we investigated the role of the regulator of T cell receptor and cytokine signaling, Ptpn2, in the formation and function of T(RM) cells in skin. Ptpn2-deficient CD8(+) T cells displayed a marked defect in genera...

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Detalles Bibliográficos
Autores principales: Hochheiser, Katharina, Wiede, Florian, Wagner, Teagan, Freestone, David, Enders, Matthias H., Olshansky, Moshe, Russ, Brendan, Nüssing, Simone, Bawden, Emma, Braun, Asolina, Bachem, Annabell, Gressier, Elise, McConville, Robyn, Park, Simone L., Jones, Claerwen M., Davey, Gayle M., Gyorki, David E., Tscharke, David, Parish, Ian A., Turner, Stephen, Herold, Marco J., Tiganis, Tony, Bedoui, Sammy, Gebhardt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091133/
https://www.ncbi.nlm.nih.gov/pubmed/33914023
http://dx.doi.org/10.1084/jem.20200940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091133/
https://www.ncbi.nlm.nih.gov/pubmed/33914023
http://dx.doi.org/10.1084/jem.20200940

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