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The Coronavirus Network Explorer: mining a large-scale knowledge graph for effects of SARS-CoV-2 on host cell function

BACKGROUND: Leveraging previously identified viral interactions with human host proteins, we apply a machine learning-based approach to connect SARS-CoV-2 viral proteins to relevant host biological functions, diseases, and pathways in a large-scale knowledge graph derived from the biomedical literat...

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Detalles Bibliográficos
Autores principales: Krämer, Andreas, Billaud, Jean-Noël, Tugendreich, Stuart, Shiffman, Dan, Jones, Martin, Green, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091149/
https://www.ncbi.nlm.nih.gov/pubmed/33941085
http://dx.doi.org/10.1186/s12859-021-04148-x