Farnesoid X receptor (FXR): Structures and ligands

Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...

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Detalles Bibliográficos
Autores principales: Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://www.ncbi.nlm.nih.gov/pubmed/33995909
http://dx.doi.org/10.1016/j.csbj.2021.04.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://www.ncbi.nlm.nih.gov/pubmed/33995909
http://dx.doi.org/10.1016/j.csbj.2021.04.029

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