Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy

PURPOSE: Despite the success of chimeric antigen receptor (CAR) T cells in clinical studies, a significant proportion of responding patients eventually relapsed, with the latter correlating with low CAR T cell expansion and persistence. METHODS AND RESULTS: Using patient-derived xenograft (PDX) mous...

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Detalles Bibliográficos
Autores principales: Xu, Ning, Tse, Benjamin, Yang, Lu, Tang, Tiffany C Y, Haber, Michelle, Micklethwaite, Kenneth, Dolnikov, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091475/
https://www.ncbi.nlm.nih.gov/pubmed/33954150
http://dx.doi.org/10.2147/ITT.S296161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091475/
https://www.ncbi.nlm.nih.gov/pubmed/33954150
http://dx.doi.org/10.2147/ITT.S296161

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