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Exosomal HMGB1 derived from hypoxia‐conditioned bone marrow mesenchymal stem cells increases angiogenesis via the JNK/HIF‐1α pathway

Mesenchymal stem cells (MSCs) have been described to induce angiogenesis in various tissues and have been used for the development of novel cell‐based therapies. Increasing evidence suggests that MSCs execute their paracrine function via the secretion of exosomes, especially under hypoxic conditions...

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Detalles Bibliográficos
Autores principales: Gao, Wenling, He, Ronghan, Ren, Jianhua, Zhang, Wenhui, Wang, Kun, Zhu, Lei, Liang, Tangzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091582/
https://www.ncbi.nlm.nih.gov/pubmed/33711197
http://dx.doi.org/10.1002/2211-5463.13142