Dapagliflozin reverses the imbalance of T helper 17 and T regulatory cells by inhibiting SGK1 in a mouse model of diabetic kidney disease

An imbalance between T helper 17 (Th17) and T regulatory (Treg) cell subsets contributes to the pathogenesis of diabetic kidney disease (DKD). However, the underlying regulatory mechanisms that cause this imbalance are unknown. Serum/glucocorticoid‐regulated kinase 1 (SGK1) has been suggested to aff...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Zhang, Zikun, Si, Zekun, Yang, Yanlin, Li, Shuangshuang, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091586/
https://www.ncbi.nlm.nih.gov/pubmed/33728820
http://dx.doi.org/10.1002/2211-5463.13147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091586/
https://www.ncbi.nlm.nih.gov/pubmed/33728820
http://dx.doi.org/10.1002/2211-5463.13147

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