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Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages

Pancreatic ductal adenocarcinoma (PDA) is accompanied by reprogramming of the local microenvironment, but changes at distal sites are poorly understood. We implanted biomaterial scaffolds, which act as an artificial premetastatic niche, into immunocompetent tumor-bearing and control mice, and identi...

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Detalles Bibliográficos
Autores principales: Kemp, Samantha B, Steele, Nina G, Carpenter, Eileen S, Donahue, Katelyn L, Bushnell, Grace G, Morris, Aaron H, The, Stephanie, Orbach, Sophia M, Sirihorachai, Veerin R, Nwosu, Zeribe C, Espinoza, Carlos, Lima, Fatima, Brown, Kristee, Girgis, Alexander A, Gunchick, Valerie, Zhang, Yaqing, Lyssiotis, Costas A, Frankel, Timothy L, Bednar, Filip, Rao, Arvind, Sahai, Vaibhav, Shea, Lonnie D, Crawford, Howard C, Pasca di Magliano, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091600/
https://www.ncbi.nlm.nih.gov/pubmed/33782087
http://dx.doi.org/10.26508/lsa.202000935