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Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a chronic autoimmune-mediated connective tissue disorder. Although the etiology of the disease remains undetermined, SSc is characterized by fibrosis and proliferative vascular lesions of the skin and internal organs. SSc involves the gastrointestinal tract in...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yuzuru, Okano, Takaichi, Yamada, Hirotaka, Akashi, Kengo, Sendo, Sho, Ueda, Yo, Morinobu, Akio, Saegusa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091711/
https://www.ncbi.nlm.nih.gov/pubmed/33941248
http://dx.doi.org/10.1186/s13075-021-02513-y