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Tim‐3 suppresses autoimmune hepatitis via the p38/MKP‐1 pathway in Th17 cells

T‐cell immunoglobulin‐ and mucin‐domain‐containing molecule‐3 (Tim‐3) mediates T‐cell suppression in various autoimmune diseases, such as chronic inflammatory liver disease. However, the regulatory effect of Tim‐3 on Th17 cells in autoimmune hepatitis (AIH) is incompletely understood. Here, we studi...

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Detalles Bibliográficos
Autores principales: Wu, Hongwei, Tang, Shiyue, Zhou, Mengya, Xue, Jiji, Yu, Zhenjun, Zhu, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091815/
https://www.ncbi.nlm.nih.gov/pubmed/33728805
http://dx.doi.org/10.1002/2211-5463.13148