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SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer

Acquired and intrinsic radioresistance remains a major challenge during the treatment of patients with colorectal cancer (CRC). Aberrant cholesterol metabolism precipitates the development of multiple cancers. Here, we report that exogenous or endogenous cholesterol enhances the radioresistance of C...

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Detalles Bibliográficos
Autores principales: Jin, Yuxiao, Chen, Zhiyuan, Dong, Jiali, Wang, Bin, Fan, Saijun, Yang, Xiaodong, Cui, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091817/
https://www.ncbi.nlm.nih.gov/pubmed/33665967
http://dx.doi.org/10.1002/2211-5463.13137