Protein phosphatases in the RNAPII transcription cycle: erasers, sculptors, gatekeepers, and potential drug targets

The transcription cycle of RNA polymerase II (RNAPII) is governed at multiple points by opposing actions of cyclin-dependent kinases (CDKs) and protein phosphatases, in a process with similarities to the cell division cycle. While important roles of the kinases have been established, phosphatases ha...

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Detalles Bibliográficos
Autores principales: Cossa, Giacomo, Parua, Pabitra K., Eilers, Martin, Fisher, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091971/
https://www.ncbi.nlm.nih.gov/pubmed/33888562
http://dx.doi.org/10.1101/gad.348315.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091971/
https://www.ncbi.nlm.nih.gov/pubmed/33888562
http://dx.doi.org/10.1101/gad.348315.121

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