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The roles and regulation of MDM2 and MDMX: it is not just about p53

Most well studied as proteins that restrain the p53 tumor suppressor protein, MDM2 and MDMX have rich lives outside of their relationship to p53. There is much to learn about how these two proteins are regulated and how they can function in cells that lack p53. Regulation of MDM2 and MDMX, which tak...

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Detalles Bibliográficos
Autores principales: Klein, Alyssa M., de Queiroz, Rafaela Muniz, Venkatesh, Divya, Prives, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091979/
https://www.ncbi.nlm.nih.gov/pubmed/33888565
http://dx.doi.org/10.1101/gad.347872.120