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DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia

Acute myeloid leukemia (AML) is a molecularly complex disease characterized by heterogeneous tumor genetic profiles and involving numerous pathogenic mechanisms and pathways. Integration of molecular data types across multiple patient cohorts may advance current genetic approaches for improved subcl...

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Detalles Bibliográficos
Autores principales: Giacopelli, Brian, Wang, Min, Cleary, Ada, Wu, Yue-Zhong, Schultz, Anna Reister, Schmutz, Maximilian, Blachly, James S., Eisfeld, Ann-Kathrin, Mundy-Bosse, Bethany, Vosberg, Sebastian, Greif, Philipp A., Claus, Rainer, Bullinger, Lars, Garzon, Ramiro, Coombes, Kevin R., Bloomfield, Clara D., Druker, Brian J., Tyner, Jeffrey W., Byrd, John C., Oakes, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092005/
https://www.ncbi.nlm.nih.gov/pubmed/33707228
http://dx.doi.org/10.1101/gr.269233.120