Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

Massively parallel reporter assays (MPRAs) are useful tools to characterize regulatory elements in human genomes. An aspect of MPRAs that is not typically the focus of analysis is their intrinsic ability to differentiate activity levels for a given sequence element when placed in both of its possibl...

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Detalles Bibliográficos
Autores principales: Roberts, Brian S., Partridge, E. Christopher, Moyers, Bryan A., Agarwal, Vikram, Newberry, Kimberly M., Martin, Beth K., Shendure, Jay, Myers, Richard M., Cooper, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092006/
https://www.ncbi.nlm.nih.gov/pubmed/33879525
http://dx.doi.org/10.1101/gr.270751.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092006/
https://www.ncbi.nlm.nih.gov/pubmed/33879525
http://dx.doi.org/10.1101/gr.270751.120

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