SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

RNA viruses that replicate in the cytoplasm often disrupt nucleocytoplasmic transport to preferentially translate their own transcripts and prevent host antiviral responses. The Sarbecovirus accessory protein ORF6 has previously been shown to be a major inhibitor of interferon production in both sev...

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Detalles Bibliográficos
Autores principales: Addetia, Amin, Lieberman, Nicole A. P., Phung, Quynh, Hsiang, Tien-Ying, Xie, Hong, Roychoudhury, Pavitra, Shrestha, Lasata, Loprieno, Michelle A., Huang, Meei-Li, Gale, Michael, Jerome, Keith R., Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092196/
https://www.ncbi.nlm.nih.gov/pubmed/33849972
http://dx.doi.org/10.1128/mBio.00065-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092196/
https://www.ncbi.nlm.nih.gov/pubmed/33849972
http://dx.doi.org/10.1128/mBio.00065-21

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