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SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98
RNA viruses that replicate in the cytoplasm often disrupt nucleocytoplasmic transport to preferentially translate their own transcripts and prevent host antiviral responses. The Sarbecovirus accessory protein ORF6 has previously been shown to be a major inhibitor of interferon production in both sev...
Autores principales: | Addetia, Amin, Lieberman, Nicole A. P., Phung, Quynh, Hsiang, Tien-Ying, Xie, Hong, Roychoudhury, Pavitra, Shrestha, Lasata, Loprieno, Michelle A., Huang, Meei-Li, Gale, Michael, Jerome, Keith R., Greninger, Alexander L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092196/ https://www.ncbi.nlm.nih.gov/pubmed/33849972 http://dx.doi.org/10.1128/mBio.00065-21 |
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