Cell-Associated HIV-1 Unspliced-to-Multiply-Spliced RNA Ratio at 12 Weeks of ART Predicts Immune Reconstitution on Therapy

Incomplete restoration of CD4(+) T-cell counts on antiretroviral therapy (ART) is a major predictor of HIV-related morbidity and mortality. To understand the possible mechanisms behind this poor immunological response despite viral suppression, we longitudinally measured more than 50 virological and...

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Detalles Bibliográficos
Autores principales: Scherpenisse, Mirte, Kootstra, Neeltje A., Bakker, Margreet, Berkhout, Ben, Pasternak, Alexander O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092199/
https://www.ncbi.nlm.nih.gov/pubmed/33688002
http://dx.doi.org/10.1128/mBio.00099-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092199/
https://www.ncbi.nlm.nih.gov/pubmed/33688002
http://dx.doi.org/10.1128/mBio.00099-21

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