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Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium

In the fight against antibiotic resistance, drugs that target resistance mechanisms in bacteria can be used to restore the therapeutic effectiveness of antibiotics. The multidrug resistance efflux complex AcrAB-TolC is the most clinically relevant efflux pump in Enterobacterales and is a target for...

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Detalles Bibliográficos
Autores principales: Wang-Kan, Xuan, Rodríguez-Blanco, Giovanny, Southam, Andrew D., Winder, Catherine L., Dunn, Warwick B., Ivens, Alasdair, Piddock, Laura J. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092203/
https://www.ncbi.nlm.nih.gov/pubmed/33785633
http://dx.doi.org/10.1128/mBio.00109-21