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The Role of Replication Clamp-Loader Protein HolC of Escherichia coli in Overcoming Replication/Transcription Conflicts

In Escherichia coli, DNA replication is catalyzed by an assembly of proteins, the DNA polymerase III holoenzyme. This complex includes the polymerase and proofreading subunits, the processivity clamp, and clamp loader complex. The holC gene encodes an accessory protein (known as χ) to the core clamp...

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Detalles Bibliográficos
Autores principales: Cooper, Deani L., Harada, Taku, Tamazi, Samia, Ferrazzoli, Alexander E., Lovett, Susan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092217/
https://www.ncbi.nlm.nih.gov/pubmed/33688004
http://dx.doi.org/10.1128/mBio.00184-21