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COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions

Beyond neutralization, antibodies binding to their Fc receptors elicit several innate immune functions including antibody-dependent complement deposition (ADCD), antibody-dependent cell-mediated phagocytosis (ADCP), and antibody-dependent cell-mediated cytotoxicity (ADCC). These functions are benefi...

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Detalles Bibliográficos
Autores principales: Adeniji, Opeyemi S., Giron, Leila B., Purwar, Mansi, Zilberstein, Netanel F., Kulkarni, Abhijeet J., Shaikh, Maliha W., Balk, Robert A., Moy, James N., Forsyth, Christopher B., Liu, Qin, Dweep, Harsh, Kossenkov, Andrew, Weiner, David B., Keshavarzian, Ali, Landay, Alan, Abdel-Mohsen, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092230/
https://www.ncbi.nlm.nih.gov/pubmed/33879594
http://dx.doi.org/10.1128/mBio.00281-21