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Cyclic di-AMP Oversight of Counter-Ion Osmolyte Pools Impacts Intrinsic Cefuroxime Resistance in Lactococcus lactis

The broadly conserved cyclic di-AMP (c-di-AMP) is a conditionally essential bacterial second messenger. The pool of c-di-AMP is fine-tuned through diadenylate cyclase and phosphodiesterase activities, and direct binding of c-di-AMP to proteins and riboswitches allows the regulation of a broad spectr...

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Detalles Bibliográficos
Autores principales: Pham, Huong Thi, Shi, Wen, Xiang, Yuwei, Foo, Su Yi, Plan, Manuel R., Courtin, Pascal, Chapot-Chartier, Marie-Pierre, Smid, Eddy J., Liang, Zhao-Xun, Marcellin, Esteban, Turner, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092236/
https://www.ncbi.nlm.nih.gov/pubmed/33832972
http://dx.doi.org/10.1128/mBio.00324-21