Mitochondrial Pyruvate Carrier Subunits Are Essential for Pyruvate-Driven Respiration, Infectivity, and Intracellular Replication of Trypanosoma cruzi

Pyruvate is the final metabolite of glycolysis and can be converted into acetyl coenzyme A (acetyl-CoA) in mitochondria, where it is used as the substrate for the tricarboxylic acid cycle. Pyruvate availability in mitochondria depends on its active transport through the heterocomplex formed by the m...

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Detalles Bibliográficos
Autores principales: Negreiros, Raquel S., Lander, Noelia, Chiurillo, Miguel A., Vercesi, Anibal E., Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092248/
https://www.ncbi.nlm.nih.gov/pubmed/33824204
http://dx.doi.org/10.1128/mBio.00540-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092248/
https://www.ncbi.nlm.nih.gov/pubmed/33824204
http://dx.doi.org/10.1128/mBio.00540-21

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