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ROP16-Mediated Activation of STAT6 Suppresses Host Cell Reactive Oxygen Species Production, Facilitating Type III Toxoplasma gondii Growth and Survival

Polymorphic effector proteins determine the susceptibility of Toxoplasma gondii strains to IFN-γ-mediated clearance mechanisms deployed by murine host cells. However, less is known about the influence of these polymorphic effector proteins on IFN-γ-independent clearance mechanisms. Here, we show tha...

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Detalles Bibliográficos
Autores principales: Kochanowsky, Joshua A., Thomas, Kaitlin K., Koshy, Anita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092286/
https://www.ncbi.nlm.nih.gov/pubmed/33653884
http://dx.doi.org/10.1128/mBio.03305-20