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Genome-Wide Analysis of Experimentally Evolved Candida auris Reveals Multiple Novel Mechanisms of Multidrug Resistance

Candida auris is globally recognized as an opportunistic fungal pathogen of high concern, due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are largely unexplored. This is the first account of genome-wide evolution of MDR in C. auris obtained through serial in vitro...

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Detalles Bibliográficos
Autores principales: Carolus, Hans, Pierson, Siebe, Muñoz, José F., Subotić, Ana, Cruz, Rita B., Cuomo, Christina A., Van Dijck, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092288/
https://www.ncbi.nlm.nih.gov/pubmed/33820824
http://dx.doi.org/10.1128/mBio.03333-20