Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System

CRISPR-Cas immune systems adapt to new threats by acquiring new spacers from invading nucleic acids such as phage genomes. However, some CRISPR-Cas loci lack genes necessary for spacer acquisition despite variation in spacer content between microbial strains. It has been suggested that such loci may...

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Detalles Bibliográficos
Autores principales: Hoikkala, Ville, Ravantti, Janne, Díez-Villaseñor, César, Tiirola, Marja, Conrad, Rachel A., McBride, Mark J., Moineau, Sylvain, Sundberg, Lotta-Riina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092290/
https://www.ncbi.nlm.nih.gov/pubmed/33785624
http://dx.doi.org/10.1128/mBio.03338-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092290/
https://www.ncbi.nlm.nih.gov/pubmed/33785624
http://dx.doi.org/10.1128/mBio.03338-20

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