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Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System
CRISPR-Cas immune systems adapt to new threats by acquiring new spacers from invading nucleic acids such as phage genomes. However, some CRISPR-Cas loci lack genes necessary for spacer acquisition despite variation in spacer content between microbial strains. It has been suggested that such loci may...
Autores principales: | Hoikkala, Ville, Ravantti, Janne, Díez-Villaseñor, César, Tiirola, Marja, Conrad, Rachel A., McBride, Mark J., Moineau, Sylvain, Sundberg, Lotta-Riina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092290/ https://www.ncbi.nlm.nih.gov/pubmed/33785624 http://dx.doi.org/10.1128/mBio.03338-20 |
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