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Bifunctional Malic/Malolactic Enzyme Provides a Novel Mechanism for NADPH-Balancing in Bacillus subtilis

The redox cofactor NADPH is required as a reducing equivalent in about 100 anabolic reactions throughout metabolism. To ensure fitness under all conditions, the demand is fulfilled by a few dehydrogenases in central carbon metabolism that reduce NADP(+) with electrons derived from the catabolism of...

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Detalles Bibliográficos
Autores principales: Hörl, Manuel, Fuhrer, Tobias, Zamboni, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092299/
https://www.ncbi.nlm.nih.gov/pubmed/33824210
http://dx.doi.org/10.1128/mBio.03438-20