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Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP(C) and Other Host-Specific Factors
Early studies in transgenic mouse lines have shown that the coexpression of endogenous murine prion protein (PrP(C)) and transgenic PrP(C) from another species either inhibits or allows the propagation of prions, depending on the infecting prion strain and interacting protein species. The way whereb...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092304/ https://www.ncbi.nlm.nih.gov/pubmed/33727358 http://dx.doi.org/10.1128/mBio.03508-20 |