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Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

Herpes simplex virus 1 (HSV-1) requires seven proteins to package its genome through a vertex in its capsid, one of which is the portal protein, pUL6. The portal protein is also thought to facilitate assembly of the procapsid. While the portal has been visualized in mature capsids, we aimed to eluci...

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Detalles Bibliográficos
Autores principales: Buch, Michael H. C., Newcomb, William W., Winkler, Dennis C., Steven, Alasdair C., Heymann, J. Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092310/
https://www.ncbi.nlm.nih.gov/pubmed/33727359
http://dx.doi.org/10.1128/mBio.03575-20