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Central Nervous System (CNS) Viral Seeding by Mature Monocytes and Potential Therapies To Reduce CNS Viral Reservoirs in the cART Era

The human immunodeficiency virus (HIV) enters the central nervous system (CNS) within a few days after primary infection, establishing viral reservoirs that persist even with combined antiretroviral therapy (cART). We show that monocytes from people living with HIV (PLWH) on suppressive cART harbori...

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Detalles Bibliográficos
Autores principales: León-Rivera, Rosiris, Veenstra, Mike, Donoso, Maribel, Tell, Elizabeth, Eugenin, Eliseo A., Morgello, Susan, Berman, Joan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092320/
https://www.ncbi.nlm.nih.gov/pubmed/33727362
http://dx.doi.org/10.1128/mBio.03633-20