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Activation of plasmacytoid dendritic cells promotes AML-cell fratricide

Acute myeloid leukemia (AML) is characterized by the proliferation of immature myeloid blasts and a suppressed immune state. Interferons have been previously shown to aid in the clearance of AML cells. Type I interferons are produced primarily by plasmacytoid dendritic cells (pDCs). However, these c...

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Detalles Bibliográficos
Autores principales: Fatehchand, Kavin, Mehta, Payal, Colvin, Christopher B., Buteyn, Nathaniel J., Santhanam, Ramasamy, Merchand-Reyes, Giovanna, Inshaar, Hafza, Shen, Brenda, Mo, Xiaokui, Mundy-Bosse, Bethany, Tridandapani, Susheela, Butchar, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092344/
https://www.ncbi.nlm.nih.gov/pubmed/33953842
http://dx.doi.org/10.18632/oncotarget.27949