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Development of Stable Chimeric IL-15 for Trans-Presentation by the Antigen Presenting Cells
IL-15 is one of the important biologics considered for vaccine adjuvant and treatment of cancer. However, a short half-life and poor bioavailability limit its therapeutic potential. Herein, we have structured IL-15 into a chimeric protein to improve its half-life enabling greater bioavailability for...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092395/ https://www.ncbi.nlm.nih.gov/pubmed/33953717 http://dx.doi.org/10.3389/fimmu.2021.646159 |