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Development of Stable Chimeric IL-15 for Trans-Presentation by the Antigen Presenting Cells

IL-15 is one of the important biologics considered for vaccine adjuvant and treatment of cancer. However, a short half-life and poor bioavailability limit its therapeutic potential. Herein, we have structured IL-15 into a chimeric protein to improve its half-life enabling greater bioavailability for...

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Detalles Bibliográficos
Autores principales:	Patidar, Manoj, Yadav, Naveen, Dalai, Sarat K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092395/ https://www.ncbi.nlm.nih.gov/pubmed/33953717 http://dx.doi.org/10.3389/fimmu.2021.646159

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