Antifungal Effect of All-trans Retinoic Acid against Aspergillus fumigatus In Vitro and in a Pulmonary Aspergillosis In Vivo Model

Aspergillus fumigatus is the most common opportunistic fungal pathogen and causes invasive pulmonary aspergillosis (IPA), with high mortality among immunosuppressed patients. The fungistatic activity of all-trans retinoic acid (ATRA) has been recently described in vitro. We evaluated the efficacy of...

Descripción completa

Detalles Bibliográficos
Autores principales: Campione, Elena, Gaziano, Roberta, Doldo, Elena, Marino, Daniele, Falconi, Mattia, Iacovelli, Federico, Tagliaferri, Daniela, Pacello, Lucrezia, Bianchi, Luca, Lanna, Caterina, Aurisicchio, Luigi, Centofanti, Federica, Di Francesco, Paolo, Del Principe, Ilaria, Del Bufalo, Francesca, Locatelli, Franco, Pistoia, Enrico Salvatore, Marra, Emanuele, Orlandi, Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092556/
https://www.ncbi.nlm.nih.gov/pubmed/33361288
http://dx.doi.org/10.1128/AAC.01874-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092556/
https://www.ncbi.nlm.nih.gov/pubmed/33361288
http://dx.doi.org/10.1128/AAC.01874-20

Ejemplares similares