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Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the Long Terminal Repeat

Macrophages are infected by human immunodeficiency virus type 1 (HIV-1) in vivo and contribute to both viral spread and pathogenesis. Recent human and animal studies suggest that HIV-1-infected macrophages serve as a reservoir that contributes to HIV-1 persistence during antiretroviral therapy. The...

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Detalles Bibliográficos
Autores principales: Viglianti, Gregory A., Planelles, Vicente, Hanley, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092691/
https://www.ncbi.nlm.nih.gov/pubmed/33472928
http://dx.doi.org/10.1128/JVI.02141-20