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Lower beta cell yield from donor pancreases after controlled circulatory death prevented by shortening acirculatory warm ischemia time and by using IGL-1 cold preservation solution

Organs from donors after controlled circulatory death (DCD III) exhibit a higher risk for graft dysfunction due to an initial period of warm ischemia. This procurement condition can also affect the yield of beta cells in islet isolates from donor pancreases, and hence their use for transplantation....

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Detalles Bibliográficos
Autores principales: De Paep, Diedert L., Van Hulle, Freya, Ling, Zhidong, Vanhoeij, Marian, Pirenne, Jacques, Keymeulen, Bart, Pipeleers, Daniel, Jacobs-Tulleneers-Thevissen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092795/
https://www.ncbi.nlm.nih.gov/pubmed/33939760
http://dx.doi.org/10.1371/journal.pone.0251055