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Genetic Determinants of Receptor-Binding Preference and Zoonotic Potential of H9N2 Avian Influenza Viruses

Receptor recognition and binding is the first step of viral infection and a key determinant of host specificity. The inability of avian influenza viruses to effectively bind human-like sialylated receptors is a major impediment to their efficient transmission in humans and pandemic capacity. Influen...

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Detalles Bibliográficos
Autores principales: Peacock, Thomas P., Sealy, Joshua E., Harvey, William T., Benton, Donald J., Reeve, Richard, Iqbal, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092835/
https://www.ncbi.nlm.nih.gov/pubmed/33268517
http://dx.doi.org/10.1128/JVI.01651-20