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Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses

Chronic neuroinflammation is observed in HIV(+) individuals on suppressive combination antiretroviral therapy (cART) and is thought to cause HIV-associated neurocognitive disorders. We recently reported that expression of HIV intron-containing RNA (icRNA) in productively infected monocyte-derived ma...

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Detalles Bibliográficos
Autores principales: Akiyama, Hisashi, Jalloh, Sallieu, Park, Seonmi, Lei, Maohua, Mostoslavsky, Gustavo, Gummuluru, Suryaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092841/
https://www.ncbi.nlm.nih.gov/pubmed/33298546
http://dx.doi.org/10.1128/JVI.01386-20