A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Antimycobacterial Activity

Global infections by nontuberculous mycobacteria (NTM) are steadily rising. New drugs are needed to treat NTM infections, but the NTM drug pipeline remains poorly populated and focused on repurposing or reformulating approved antibiotics. We sought to accelerate de novo NTM drug discovery by testing...

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Detalles Bibliográficos
Autores principales: Ganapathy, Uday S., González del Rio, Rubén, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092876/
https://www.ncbi.nlm.nih.gov/pubmed/33558292
http://dx.doi.org/10.1128/AAC.02420-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092876/
https://www.ncbi.nlm.nih.gov/pubmed/33558292
http://dx.doi.org/10.1128/AAC.02420-20

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