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Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis

Tuberculosis, caused by Mycobacterium tuberculosis, is an urgent global health problem requiring new drugs, new drug targets, and an increased understanding of antibiotic resistance. We have determined the mode of resistance to be a series of arylamide compounds in M. tuberculosis. We isolated M. tu...

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Detalles Bibliográficos
Autores principales: Shelton, Catherine D., McNeil, Matthew B., Early, Julie V., Ioerger, Thomas R., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092897/
https://www.ncbi.nlm.nih.gov/pubmed/33619059
http://dx.doi.org/10.1128/AAC.02334-20