Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization

Vaccines of outstanding efficiency, safety, and public acceptance are needed to halt the current SARS-CoV-2 pandemic. Concerns include potential side effects caused by the antigen itself and safety of viral DNA and RNA delivery vectors. The large SARS-CoV-2 spike (S) protein is the main target of cu...

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Detalles Bibliográficos
Autores principales: Hennrich, Alexandru A., Sawatsky, Bevan, Santos-Mandujano, Rosalía, Banda, Dominic H., Oberhuber, Martina, Schopf, Anika, Pfaffinger, Verena, Wittwer, Kevin, Riedel, Christiane, Pfaller, Christian K., Conzelmann, Karl-Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092985/
https://www.ncbi.nlm.nih.gov/pubmed/33882114
http://dx.doi.org/10.1371/journal.ppat.1009064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092985/
https://www.ncbi.nlm.nih.gov/pubmed/33882114
http://dx.doi.org/10.1371/journal.ppat.1009064

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