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Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization
Vaccines of outstanding efficiency, safety, and public acceptance are needed to halt the current SARS-CoV-2 pandemic. Concerns include potential side effects caused by the antigen itself and safety of viral DNA and RNA delivery vectors. The large SARS-CoV-2 spike (S) protein is the main target of cu...
Autores principales: | Hennrich, Alexandru A., Sawatsky, Bevan, Santos-Mandujano, Rosalía, Banda, Dominic H., Oberhuber, Martina, Schopf, Anika, Pfaffinger, Verena, Wittwer, Kevin, Riedel, Christiane, Pfaller, Christian K., Conzelmann, Karl-Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092985/ https://www.ncbi.nlm.nih.gov/pubmed/33882114 http://dx.doi.org/10.1371/journal.ppat.1009064 |
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