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Population Pharmacokinetics of CC-122

BACKGROUND: CC-122 is a cereblon-modulating agent that exerts direct cell-autonomous activity against malignant B cells and immunomodulatory effects. Herein, a population pharmacokinetic (popPK) model of CC-122 was developed and the influence of demographic and disease-related covariates on populati...

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Detalles Bibliográficos
Autores principales: Cheng, Yiming, Chen, Jian, Pourdehnad, Michael, Zhou, Simon, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093142/
https://www.ncbi.nlm.nih.gov/pubmed/33958900
http://dx.doi.org/10.2147/CPAA.S310604