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MiR-195-5p Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulating the PTEN-AKT Signaling Pathway

BACKGROUND: MiR-195-5p has been shown to play crucial roles in tumor inhibition, but its biological functions in cerebral ischemia-reperfusion (I/R) injury are unclear. METHODS: To mimic cerebral I/R injury, mice were induced by transient middle cerebral artery occlusion (MCAO). Human brain microvas...

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Detalles Bibliográficos
Autores principales: Ren, Xiaoli, Wang, Zhiyun, Guo, Congfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093143/
https://www.ncbi.nlm.nih.gov/pubmed/33958865
http://dx.doi.org/10.2147/NDT.S297975